Data

Silver Studies

In-Vitro Studies:

Demonstrating the Superiority of WoundForce™

pH Studies

WoundForce™ maintains its effectiveness across a wider pH range than Santyl

Purpose: compare the performance of WoundForce to Santyl in varying pH environments.

Procedure: study effects of WoundForce and Santyl on denatured proteins in differing pH solutions ranging from pH 5 to pH 9.

Results: WoundForce is not affected by pH and in all cases is 2x more active than Santyl® in vitro.

Silver Studies

WoundForce™ is compatible with
silver-based dressings, unlike Santyl

Purpose: confirm that WoundForce is not adversely affected by silver, which would lead to contraindication.

Procedure: study effects of WoundForce when used in combination with Acticoat 7 (silver-coated antimicrobial dressing).

Results:  no evidence of silver interfering with WoundForce’s ability to dissolve protein.

In-Vitro and Animal Studies:
WoundForce™ vs. Santyl

For both soft and hard eschar, WoundForce™ starts debridement earlier
than Santyl and works more efficiently once debridement begins.

Soft Eschar

              0              5              10               15               20

Eschar Survival

100%

80%

60%

40%

20%

0%

Hard Eschar

Eschar Survival

100%

80%

60%

40%

20%

0%

              0              5              10               15               20

Liquid WoundForce™

Xanthan Gum WoundForce™

Santyl

Time (days)

Time (days)